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Sunday, 30 January 2011

Particle size Analysis

Primary Characteristics - relating to basic material properties, particulate size shape and SA

Secondary Characteristics - Bahavioural properties such as flow, bulk and tapped density, compactibility, lubricity

particle shape terminology
  • Acicular: needle-shaped
  • anglular: sharped edged ; having a roughly polyhedral shape
  • fibrous: thread-like
  • Flaky: plate-like
  • Granular : irregular but approximately spherical overall form
  • irregular: lacking of symmetry
  • Modular : rounded, irregularl shape.

Thickness: the height of the particle ---> when it is resting in its position of max stability

Breath ( width) : minimum distance b/w the two tangential plane- perpendicular to defining the thickness and breadth.

length : the distance b/w 2 planes which are perpendricular to those defining the thickness and the breadth.

Shape factors

circularity

dissolution

range of particle size and units

individual particle characteristics

measures of particle size

- volume equivalent sphere

-volume equivalent diameter

ESD?

- Arithmetic mean

- Geometric mean

- surface mean diameter (SMD)

-VMD

- volume-number mean diameter (VSMD)

particle sizing of powder

Particle size distribution

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